Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl Alcohol → 3-(5-Fluorobenzothiazol-2-yl-trans-ethenyl)benzyl alcohol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl Alcohol | HCID 244 | — |
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | Isophthalaldehyde | HCID 34777 | — |
| 반응물 | 5-Fluoro-2-methylbenzothiazole | HCID 597437 | — |
| 반응물 | Sodium borohydride | HCID 4311764 | — |
| 반응물 | 3-(5-Fluorobenzothiazol-2-yl-trans-ethenyl)benzaldehyde | HCID 86747932 | — |
| 촉매 | Zincchloride | HCID 3007855 | — |
| 용매 | O-Xylene | HCID 7237 | — |
| 생성물 | 3-(5-Fluorobenzothiazol-2-yl-trans-ethenyl)benzyl alcohol | HCID 67828433 | — |
반응 단계
An alternate procedure for preparing this benzyl alcohol comprises condensing isophthalaldehyde with 2-methyl-5-fluorobenzothiazole in the presence of acetic anhydride and zinc chloride in hot xylene followed by the reduction of the 3-(5-fluorobenzothiazol-2-yl-trans-ethenyl)benzaldehyde product with sodium borohydride to provide the appropriate benzyl alcohol.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05322847 |
| 출처 데이터셋 | uspto-grants-1994_06 |
| ORD ID | ord-bebd70f669a54af8be82f17d90119462 |
| 출처 메모 | uspto-grants-1994_06 |