Bromine → HCID 86744381, 화합물

HRID 1110679노트

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HRID 1110679 반응식
[Br-:1].[OH:2][CH2:3][CH2:4][N+:5]([CH3:8])([CH3:7])[CH3:6].BrBr>O>[Br-:1].[Br-:1].[Br-:1].[OH:2][CH2:3][CH2:4][N+:5]([CH3:8])([CH3:7])[CH3:6].[OH:2][CH2:3][CH2:4][N+:5]([CH3:8])([CH3:7])[CH3:6].[OH:2][CH2:3][CH2:4][N+:5]([CH3:8])([CH3:7])[CH3:6]

참가 물질

4

반응물 2

HCID 24408BromineHCID 74724Choline Bromide

생성물 1

HCID 86744381HCID 86744381, 화합물

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
50 °C

실험 절차

The recrystallized N-(2-hydroxyethyl)-N,N,N-trimethylammonium bromide (55.86 grams, 0.30 moles) was placed in a 100 ml flask fitted with a magnetic stirrer and a pressure equalizing addition funnel. Water (29 ml) was added to make a 50% solution and the solution was stirred vigorously while 48.5 grams (0.30 moles) of bromine was added dropwise from the addition funnel. The tribromide fell out of solution as a dark red oil. The product was separated from the aqueous layer by decantation and the residual water removed by warming to 50° C. at aspirator pressure for fifteen minutes. The yield of N-(2-hydroxyethyl)-N,N,N-trimethylammonium tribromide was 103.16 grams. Analysis: %Brtot =67.63 (exp), 69.71 (theo); %Brox =44.10 (exp), 46.41 (theo).

후처리

  1. customfitted with a magnetic stirrer
  2. additionaddition funnel
  3. additionwas added dropwise from the addition funnel
  4. customThe product was separated from the aqueous layer by decantation
  5. customthe residual water removed

출처 및 근거

ORD 기록
ord-2e483024f187451db537f0d1df3e35fb
출처 데이터셋
uspto-grants-1990_12
특허 번호
US04976874

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