HCID 14552383, 화합물 → HCID 14552384, 화합물
반응식
C1(C[NH:8][CH:9]2[CH2:18][CH2:17][C:12]3([O:16][CH2:15][CH2:14][O:13]3)[CH2:11][CH:10]2[C:19]([O:21][CH2:22][CH3:23])=[O:20])C=CC=CC=1>[Pd].C(O)C>[NH2:8][CH:9]1[CH2:18][CH2:17][C:12]2([O:16][CH2:15][CH2:14][O:13]2)[CH2:11][CH:10]1[C:19]([O:21][CH2:22][CH3:23])=[O:20]참가 물질
4
실험 절차
Ethyl 8-[(phenylmethyl)amino]-1,4-dioxaspiro[4.5]-decane-7-carboxylate (397.2 g, 1.3 mole) was combined with 2563 ml of ethanol and 80 g of 5% palladium on activated carbon and hydrogenated at 50 p.s.i. for 6 hours at 45°-50° C. The catalyst was separated by filtration, and the filtrate was evaporated. When taken up in methylene chloride a semi-solid precipitated and was filtered out. The filtrate was evaporated to yield 277.7 g (97.4%) of the title product.
후처리
- customThe catalyst was separated by filtration
- customthe filtrate was evaporated
- customprecipitated
- filtrationwas filtered out
- customThe filtrate was evaporated
출처 및 근거
- ORD 기록
- ord-322f95e883334a8c8447fd7adf8ef6bc
- 출처 데이터셋
- uspto-grants-1990_12
- 특허 번호
- US04977160
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