Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,1'-Carbonyldiimidazole → 9-chloro-1(dimethylaminoethyl)-7-phenylpyrimido[1,2-a][1,4]-benzodiazepin-3(5H)-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| 반응물 | N-Desmethyl-N(4)-desoxychlordiazepoxide | HCID 165626 | — |
| 반응물 | tetrahydrofuran N,N-dimethylformamide | HCID 21974620 | — |
| 생성물 | 9-chloro-1(dimethylaminoethyl)-7-phenylpyrimido[1,2-a][1,4]-benzodiazepin-3(5H)-one | HCID 22153726 | — |
반응 단계
In the manner given in Example 16, carbonyldiimidazole, 4-dimethylamino-butyn-2-oic acid and 2-amino-7-chloro-5-phenyl-3H-1,4-benzodiazepine was stirred in tetrahydrofuran-dimethylformamide to give 9-chloro-1(dimethylaminoethyl)-7-phenylpyrimido[1,2-a][1,4]-benzodiazepin-3(5H)-one.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04978753 |
| 출처 데이터셋 | uspto-grants-1990_12 |
| ORD ID | ord-2af7079530fa421d8f6674cac9a77390 |
| 출처 메모 | uspto-grants-1990_12 |