Ethylamine → N-Ethyl-p-toluenesulfonamide
반응식
[CH3:1][C:2]1[CH:7]=[CH:6][C:5]([S:8](Cl)(=[O:10])=[O:9])=[CH:4][CH:3]=1.[CH2:12]([NH2:14])[CH3:13]>O>[CH2:12]([NH:14][S:8]([C:5]1[CH:6]=[CH:7][C:2]([CH3:1])=[CH:3][CH:4]=1)(=[O:10])=[O:9])[CH3:13]참가 물질
4
반응 조건
- 온도
- 0 °C
실험 절차
A suspension of 26 g of paratoluene sulfochloride in 200 cm3 of water is cooled to 0° C. With stirring there are slowly added 100 cm3 of a 40% aqueous solution of ethylamine in water. At the end of the addition the reaction mixture is again stirred for two hours at 0° C., then for two hours at ambient temperature. The solid in suspension is filtered, washed several times with water, then dried under reduced pressure. 24 g of N-ethyl(4-methyl phenyl) sulfonamide are obtained.
후처리
- additionAt the end of the addition the reaction mixture
- stirringis again stirred for two hours at 0° C.
- filtrationThe solid in suspension is filtered
- washwashed several times with water
- customdried under reduced pressure
출처 및 근거
- ORD 기록
- ord-d599a79aa3e64d06827e17c0f9d941d0
- 출처 데이터셋
- uspto-grants-1990_12
- 특허 번호
- US04980509
반응 노트
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