2,4,6-Trifluorobenzyl alcohol → (RS)-5-oxo-1-[4-(2,4,6-trifluoro-benzyloxy)-phenyl]-pyrrolidine-3-carboxylic acid methyl ester

반응식

[CH3:1][O:2][C:3](=[O:4])[CH:5]1[CH2:6][N:7]([c:11]2[cH:12][cH:13][c:14]([OH:17])[cH:15][cH:16]2)[C:8](=[O:10])[CH2:9]1.[F:18][c:19]1[c:20]([CH2:21][OH:22])[c:23]([F:28])[cH:24][c:25]([F:27])[cH:26]1>>[CH3:1][O:2][C:3](=[O:4])[CH:5]1[CH2:6][N:7]([c:11]2[cH:12][cH:13][c:14]([O:17][CH2:21][c:20]3[c:19]([F:18])[cH:26][c:25]([F:27])[cH:24][c:23]3[F:28])[cH:15][cH:16]2)[C:8](=[O:10])[CH2:9]1

참가 물질

반응물 2

HCID 27770372,4,6-Trifluorobenzyl alcohol

HCID 2883518Methyl 1-(4-hydroxyphenyl)-5-oxopyrrolidine-3-carboxylate

생성물 1

HCID 68614540(RS)-5-oxo-1-[4-(2,4,6-trifluoro-benzyloxy)-phenyl]-pyrrolidine-3-carboxylic acid methyl ester

출처 및 근거

ORD 기록: ord-33ea3422494146718e9d045e8488eeb1
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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