2-Piperidino-4-imino-2-thiazoline hydrochloride → HCID 178425434, 화합물

반응식

[Cl:1][C:2]1[C:3]([F:15])=[C:4]2[C:8](=[C:9]([F:12])[C:10]=1[F:11])[C:7](=[NH:13])[NH:6][C:5]2=N.Cl.[CH3:17][CH:18]1[CH2:23][CH2:22][CH2:21][CH2:20][N:19]1[C:24]1[S:25][CH2:26][C:27](=[NH:29])[N:28]=1.Cl.N1(C2SCC(=N)N=2)CCCCC1>>[ClH:1].[NH:13]=[C:7]1[C:8]2[C:4](=[C:3]([F:15])[C:2]([Cl:1])=[C:10]([F:11])[C:9]=2[F:12])[C:5](=[C:26]2[S:25][C:24]([N:19]3[CH2:20][CH2:21][CH2:22][CH2:23][CH:18]3[CH3:17])=[N:28][C:27]2=[NH:29])[NH:6]1

참가 물질

반응물 3

HCID 162452962-Piperidino-4-imino-2-thiazoline hydrochloride

HCID 227642352-(2-Methylpiperidino)-4-imino-2-thiazoline hydrochloride

HCID 178508683HCID 178508683, 화합물

생성물 1

HCID 178425434HCID 178425434, 화합물

실험 절차

Following the procedure described in Example 9, part B above but using equivalent amounts of 5-chloro-4,6,7-trifluoro-1,3-diiminoisoindoline and 2-(2-methylpiperidino)-4-imino-2-thiazoline hydrochloride in place of 1,3-diiminoisoindoline and 2-piperidino-4-imino-2-thiazoline hydrochloride respectively, there is obtained as the product 1-imino-5-chloro-4,6,7-trifluoro-3-[2-(2-methylpiperidino)-4-imino-2-thiazolin-5-ylidene]isoindoline hydrochloride.