Tetrahydrofuran → 4-{7-[3-(2-Oxo-pyrrolidin-1-yl)-propoxy]-quinazolin-4-yl}-piperidine-1-carboxylic acid tert-butyl ester

HRID 1113249

반응식

HRID 1113249 반응식
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([F:24])[cH:21][cH:22][c:23]23)[CH2:12][CH2:13]1.[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[OH:25][CH2:26][CH2:27][CH2:28][N:29]1[C:30](=[O:34])[CH2:31][CH2:32][CH2:33]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([c:14]2[n:15][cH:16][n:17][c:18]3[cH:19][c:20]([O:25][CH2:26][CH2:27][CH2:28][N:29]4[C:30](=[O:34])[CH2:31][CH2:32][CH2:33]4)[cH:21][cH:22][c:23]23)[CH2:12][CH2:13]1

참가 물질

4

반응물 3

HCID 8028TetrahydrofuranHCID 5667441-(3-Hydroxypropyl)pyrrolidin-2-oneHCID 595517364-(7-Fluoro-quinazolin-4-yl)-piperidine-1-carboxylic acid tert-butyl ester

생성물 1

HCID 595517034-{7-[3-(2-Oxo-pyrrolidin-1-yl)-propoxy]-quinazolin-4-yl}-piperidine-1-carboxylic acid tert-butyl ester

출처 및 근거

ORD 기록
ord-f8fb9e8af5a84bd58de7380a16751376
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

연결된 노트

불러오는 중…