1-(4-Difluoromethoxy-3-methyl-phenyl)-ethanone → (RS)-1-(3-bromo-5-ethoxymethyl-phenyl)-1-(4-difluoromethoxy-3-methyl-phenyl)-ethanol
반응식
[Br:15][c:16]1[cH:17][c:18]([Br:26])[cH:19][c:20]([CH2:22][O:23][CH2:24][CH3:25])[cH:21]1.[CH2:27]([Li:28])[CH2:29][CH2:30][CH3:31].[F:1][CH:2]([O:3][c:4]1[c:5]([CH3:13])[cH:6][c:7]([C:10]([CH3:11])=[O:12])[cH:8][cH:9]1)[F:14]>>[F:1][CH:2]([O:3][c:4]1[c:5]([CH3:13])[cH:6][c:7]([C:10]([CH3:11])([OH:12])[c:16]2[cH:17][c:18]([Br:26])[cH:19][c:20]([CH2:22][O:23][CH2:24][CH3:25])[cH:21]2)[cH:8][cH:9]1)[F:14]참가 물질
4
출처 및 근거
- ORD 기록
- ord-68e1eed32e4d41649c4a7b7589418812
- 출처 데이터셋
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
반응 노트
불러오는 중…