(4-(Methylsulfinyl)phenyl)boronic acid → [2,6-Difluoro-4-(4-methylsulfinylphenyl)phenyl]-[2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone

HRID 1116356

반응식

HRID 1116356 반응식
[Br:13][c:14]1[cH:15][c:16]([F:34])[c:17]([C:21](=[O:22])[N:23]2[CH:24]([CH2:28][N:29]3[CH2:30][CH2:31][CH2:32][CH2:33]3)[CH2:25][CH2:26][CH2:27]2)[c:18]([F:20])[cH:19]1.[CH3:1][S:2](=[O:3])[c:4]1[cH:5][cH:6][c:7]([B:10]([OH:11])[OH:12])[cH:8][cH:9]1>>[CH3:1][S:2](=[O:3])[c:4]1[cH:5][cH:6][c:7](-[c:14]2[cH:15][c:16]([F:34])[c:17]([C:21](=[O:22])[N:23]3[CH:24]([CH2:28][N:29]4[CH2:30][CH2:31][CH2:32][CH2:33]4)[CH2:25][CH2:26][CH2:27]3)[c:18]([F:20])[cH:19]2)[cH:8][cH:9]1

참가 물질

3

반응물 2

HCID 2773531(4-(Methylsulfinyl)phenyl)boronic acidHCID 11964889(4-Bromo-2,6-difluorophenyl)-[2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone

생성물 1

HCID 57980029[2,6-Difluoro-4-(4-methylsulfinylphenyl)phenyl]-[2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone

출처 및 근거

ORD 기록
ord-4d2e47a67bbf47cca79101e61a4224a7
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

연결된 노트

불러오는 중…