3-Fluorobenzyl bromide → 6-Fluoro-1-(3-fluorobenzyl)-2-oxo-4-[4-(thiophene-2-carbonyl)-piperazin-1-yl]-1,2-dihydro-[1,8]-naphthyridine-3-carboxylic acid ethyl ester

HRID 1118018

반응식

HRID 1118018 반응식
[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7](=[O:30])[nH:8][c:9]2[n:10][cH:11][c:12]([F:29])[cH:13][c:14]2[c:15]1[N:16]1[CH2:17][CH2:18][N:19]([C:22](=[O:23])[c:24]2[s:25][cH:26][cH:27][cH:28]2)[CH2:20][CH2:21]1.[F:31][c:32]1[cH:33][c:34]([CH2:35][Br:36])[cH:37][cH:38][cH:39]1>>[CH2:1]([CH3:2])[O:3][C:4](=[O:5])[c:6]1[c:7](=[O:30])[n:8]([CH2:35][c:34]2[cH:33][c:32]([F:31])[cH:39][cH:38][cH:37]2)[c:9]2[n:10][cH:11][c:12]([F:29])[cH:13][c:14]2[c:15]1[N:16]1[CH2:17][CH2:18][N:19]([C:22](=[O:23])[c:24]2[s:25][cH:26][cH:27][cH:28]2)[CH2:20][CH2:21]1

참가 물질

3

반응물 2

HCID 680073-Fluorobenzyl bromideHCID 692171586-Fluoro-2-oxo-4-[4-(thiophene-2-carbonyl)-piperazin-1-yl]-1,2-dihydro-[1,8]-naphthyridine-3-carboxylic Acid Ethyl Ester

생성물 1

HCID 596995976-Fluoro-1-(3-fluorobenzyl)-2-oxo-4-[4-(thiophene-2-carbonyl)-piperazin-1-yl]-1,2-dihydro-[1,8]-naphthyridine-3-carboxylic acid ethyl ester

출처 및 근거

ORD 기록
ord-8622cae475dc4a40948833f6e47ea4ac
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

연결된 노트

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