1,1-Dimethylethyl 5-bromo-2-(methyloxy)-3-pyridinecarboxylate → Tert-butyl 5-(3,5-dimethylpiperazin-1-yl)-2-methoxypyridine-3-carboxylate

반응식

[Br:16][c:17]1[cH:18][c:19]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[c:20]([O:23][CH3:24])[n:21][cH:22]1.[Cl:1][c:2]1[cH:3][c:4]([N:8]2[CH2:9][CH:10]([CH3:15])[NH:11][CH:12]([CH3:14])[CH2:13]2)[cH:5][cH:6][n:7]1>>[N:8]1([c:17]2[cH:18][c:19]([C:25](=[O:26])[O:27][C:28]([CH3:29])([CH3:30])[CH3:31])[c:20]([O:23][CH3:24])[n:21][cH:22]2)[CH2:9][CH:10]([CH3:15])[NH:11][CH:12]([CH3:14])[CH2:13]1

참가 물질

반응물 2

HCID 589881461,1-Dimethylethyl 5-bromo-2-(methyloxy)-3-pyridinecarboxylate

HCID 724825601-(2-Chloro-4-pyridinyl)-3,5-dimethylpiperazine

생성물 1

HCID 68681397Tert-butyl 5-(3,5-dimethylpiperazin-1-yl)-2-methoxypyridine-3-carboxylate

출처 및 근거

ORD 기록: ord-f0ce51ffd7c64ff0b9b38b6be459dc3c
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

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