2-Amino-N,2-dimethylpropanamide → 6-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (1-methyl-1-methylcarbamoyl-ethyl)-amide

반응식

[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:19])([F:20])[CH2:18]3)[cH:8][cH:9][c:10]([C:12](=[O:13])[OH:14])[n:11]2)[CH2:2][CH2:3]1.[NH2:21][C:22]([C:23](=[O:24])[NH:25][CH3:26])([CH3:27])[CH3:28]>>[CH:1]1([CH2:4][O:5][c:6]2[c:7]([N:15]3[CH2:16][C:17]([F:19])([F:20])[CH2:18]3)[cH:8][cH:9][c:10]([C:12](=[O:14])[NH:21][C:22]([C:23](=[O:24])[NH:25][CH3:26])([CH3:27])[CH3:28])[n:11]2)[CH2:2][CH2:3]1

참가 물질

반응물 2

HCID 187922142-Amino-N,2-dimethylpropanamide

HCID 710872926-(Cyclopropylmethoxy)-5-(3,3-difluoroazetidin-1-yl)picolinic acid

생성물 1

HCID 711131966-Cyclopropylmethoxy-5-(3,3-difluoro-azetidin-1-yl)-pyridine-2-carboxylic acid (1-methyl-1-methylcarbamoyl-ethyl)-amide

출처 및 근거

ORD 기록: ord-44b3539337bb44a1a62b159a0ac9bccc
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

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