Water → 4,8-Dimethylnona-3,7-dien-2-yl butanoate

HRID 11191

반응식

HRID 11191 반응식
[CH3:1][C:2]([CH2:7][CH2:8][CH:9]=[C:10]([CH3:12])[CH3:11])=[CH:3][CH:4]([OH:6])[CH3:5].N1C=[CH:17][CH:16]=[CH:15][CH:14]=1.[OH2:19]>C(OC)(C)(C)C>[C:14]([O:6][CH:4]([CH:3]=[C:2]([CH3:1])[CH2:7][CH2:8][CH:9]=[C:10]([CH3:11])[CH3:12])[CH3:5])(=[O:19])[CH2:15][CH2:16][CH3:17]

참가 물질

5

반응물 3

HCID 962WaterHCID 1049PyridineHCID 1068744,8-Dimethylnona-3,7-dien-2-ol

생성물 1

HCID 713673054,8-Dimethylnona-3,7-dien-2-yl butanoate수율 76%

시약·촉매·용매 1

HCID 15413tert-Butyl methyl ether용매

반응 조건

온도
100 °C

실험 절차

A flask was charged with 4,8-dimethyl-3,7-nonadien-2-ol CAS 67845-50-5 (20 grams), buryric anhydride (25 grams) and pyridine (12.5 grams). The mixture was stirred and heated to 100° C. The reaction was held at 100° C.±1° C. for 90 minutes and then cooled to room temperature. The reaction mixture was diluted with water (100 milliliters) and methyl t-butyl ether, washed several times with water until neutral pH, dried over sodium sulfate and concentrated to furnish 34.4 grams of crude product. After distillation by Kugelruhr 23.4 g of the product, 76% yield, were obtained and confirmed by 1H NMR.

후처리

  1. temperaturecooled to room temperature
  2. washwashed several times with water until neutral pH
  3. dry with materialdried over sodium sulfate
  4. concentrationconcentrated

출처 및 근거

ORD 기록
ord-b29dfb38e38e4655b60cb3c4a305e099
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07097872B2

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