Potassium Carbonate → N,N'-diphenyl-N-(3-tolyl)-1,4-phenylenediamine

HRID 11195

반응식

HRID 11195 반응식
[C:1]1([N:7]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[C:8]2[CH:13]=[CH:12][C:11]([NH2:14])=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.I[C:22]1[CH:23]=[C:24](C)[CH:25]=[CH:26][CH:27]=1.[C:29](=O)([O-])[O-].[K+].[K+]>[Cu].C1C2C(CCCC2)CCC1>[C:1]1([N:7]([C:15]2[CH:20]=[C:19]([CH3:29])[CH:18]=[CH:17][CH:16]=2)[C:8]2[CH:13]=[CH:12][C:11]([NH:14][C:22]3[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=3)=[CH:10][CH:9]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

참가 물질

6

반응물 3

HCID 11430Potassium CarbonateHCID 122683-IodotolueneHCID 75371N,N-Diphenyl-p-phenylenediamine

생성물 1

HCID 21972152N,N'-diphenyl-N-(3-tolyl)-1,4-phenylenediamine수율 48.6%

시약·촉매·용매 2

HCID 23978Copper촉매HCID 7044Decalin용매

실험 절차

In a 200 ml reaction vessel 26 grams of N,N-diphenyl-1,4-phenylenediamine and 22 grams of 3-iodotoluene were heated together with 0.3 grams of activated copper powders, 50 grams of potassium carbonate and 50 ml of decalin at an oil bath temperature of 200° C. for 24 hours in an Ar atmosphere. After the completion of the reaction, the reaction solution was filtrated with the addition of 100 ml of toluene thereto, thereby removing insolubles. The filtrate was washed with water, and dried over sodium sulfate. Following this, the solvent was removed by distillation from the filtrate, and the residue was purified twice by means of a silica gel column (using a mixed solvent of n-hexane and toluene as a developing solvent), thereby obtaining 17 grams of N,N′-diphenyl-N-(3-tolyl)-1,4-phenylenediamine.

후처리

  1. customAfter the completion of the reaction
  2. filtrationthe reaction solution was filtrated with the addition of 100 ml of toluene
  3. washThe filtrate was washed with water
  4. dry with materialdried over sodium sulfate
  5. customwas removed by distillation from the filtrate
  6. customthe residue was purified twice by means of a silica gel column (

출처 및 근거

ORD 기록
ord-ecdbda356a6f4cedb55b2effebef9de2
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07097918B2

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