Benzene → 1,2-Epoxy-3-tridecanol
반응식
[CH2:1]=[CH:2][CH:3]([OH:14])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13].ClC1C=CC=C(C(OO)=[O:23])C=1.C1C=CC=CC=1>CCCCCC>[O:23]1[CH:2]([CH:3]([OH:14])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH3:13])[CH2:1]1참가 물질
5
실험 절차
A 500-ml flask equipped with a stirrer was charged with 23.8 g (0.12 mol) of 1-tridecen-3-ol, 25.0 g (0.145 mol) of m-chloroperbenzoic acid and 250 ml of benzene, and the contents were stirred at room temperature for 48 hours. After completion of the reaction, 200 ml of hexane. Solids deposited were separated by filtration, and the solvent was distilled off under reduced pressure. The resultant residue was purified by column chromatography on silica gel, thereby obtaining 19.0 g (yield: 74%) of 1,2-epoxy-3-tridecanol.
후처리
- customA 500-ml flask equipped with a stirrer
- customSolids deposited were separated by filtration
- distillationthe solvent was distilled off under reduced pressure
- customThe resultant residue was purified by column chromatography on silica gel
출처 및 근거
- ORD 기록
- ord-336388df5b80425486bbf74ea75cd7c9
- 출처 데이터셋
- uspto-grants-1998_03
- 특허 번호
- US05723497
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