3-Pyridinecarboxaldehyde → 6-[8-(Pyridin-3-ylmethyl)-3,8-diazabicyclo[3.2.1]octan-3-yl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine

반응식

[CH:9]12[CH2:10][N:11]([c:17]3[cH:18][cH:19][c:20]4[n:21]([n:22]3)[c:23]([C:26]([F:27])([F:28])[F:29])[n:24][n:25]4)[CH2:12][CH:13]([CH2:14][CH2:15]1)[NH:16]2.[n:1]1[cH:2][c:3]([CH:7]=[O:8])[cH:4][cH:5][cH:6]1>>[n:1]1[cH:2][c:3]([CH2:7][N:16]2[CH:9]3[CH2:10][N:11]([c:17]4[cH:18][cH:19][c:20]5[n:21]([n:22]4)[c:23]([C:26]([F:27])([F:28])[F:29])[n:24][n:25]5)[CH2:12][CH:13]2[CH2:14][CH2:15]3)[cH:4][cH:5][cH:6]1

참가 물질

반응물 2

HCID 103713-Pyridinecarboxaldehyde

HCID 772700266-(3,8-Diazabicyclo[3.2.1]octan-3-yl)-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine

생성물 1

HCID 725292556-[8-(Pyridin-3-ylmethyl)-3,8-diazabicyclo[3.2.1]octan-3-yl]-3-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine

출처 및 근거

ORD 기록: ord-c3c452020013402b9cf3477449f9b4a4
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…