3-[2-(3-{[tert-Butyl(dimethyl)silyl]oxy}-2,2-dimethylpropyl)-4-formyl-1-oxo-1,2-dihydroisoquinolin-6-yl]-N-cyclopropyl-5-fluoro-4-methylbenzamide → 3-[2-(3-{[tert-Butyl(dimethyl)silyl]oxy}-2,2-dimethylpropyl)-4-(1-hydroxyethyl)-1-oxo-1,2-dihydroisoquinolin-6-yl]-N-cyclopropyl-5-fluoro-4-methylbenzamide

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][C:8]([CH2:9][n:10]1[c:11](=[O:36])[c:12]2[cH:13][cH:14][c:15](-[c:22]3[cH:23][c:24]([C:25](=[O:26])[NH:27][CH:28]4[CH2:29][CH2:30]4)[cH:31][c:32]([F:35])[c:33]3[CH3:34])[cH:16][c:17]2[c:18]([CH:20]=[O:21])[cH:19]1)([CH3:37])[CH3:38])([CH3:39])[CH3:40].[CH3:41][Mg:42][Cl:43]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH2:7][C:8]([CH2:9][n:10]1[c:11](=[O:36])[c:12]2[cH:13][cH:14][c:15](-[c:22]3[cH:23][c:24]([C:25](=[O:26])[NH:27][CH:28]4[CH2:29][CH2:30]4)[cH:31][c:32]([F:35])[c:33]3[CH3:34])[cH:16][c:17]2[c:18]([CH:20]([OH:21])[CH3:41])[cH:19]1)([CH3:37])[CH3:38])([CH3:39])[CH3:40]