Water → Tert-butyl 4-[(6-bromo-2-{[1-({[tert-butyl(dimethyl)silyl]oxy}methyl)cyclopropyl]methyl}-1-oxo-1,2-dihydroisoquinolin-4-yl)sulfonyl]-1,4-diazepane-1-carboxylate

HRID 1121474노트

반응식

[Br:1][c:2]1[cH:3][c:4]2[c:5]([S:13](=[O:14])(=[O:15])[N:16]3[CH2:17][CH2:18][N:19]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:20][CH2:21][CH2:22]3)[cH:6][nH:7][c:8](=[O:12])[c:9]2[cH:10][cH:11]1.[C:48](=[O:49])([O-:50])[O-:51].[CH3:30][S:31]([O:32][CH2:35][C:36]1([CH2:39][O:40][Si:41]([CH3:42])([CH3:43])[C:44]([CH3:45])([CH3:46])[CH3:47])[CH2:37][CH2:38]1)(=[O:33])=[O:34].[Cs+:52].[Cs+:53].[O:54]=[CH:55][N:56]([CH3:57])[CH3:58].[OH2:59]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([S:13](=[O:14])(=[O:15])[N:16]3[CH2:17][CH2:18][N:19]([C:23](=[O:24])[O:25][C:26]([CH3:27])([CH3:28])[CH3:29])[CH2:20][CH2:21][CH2:22]3)[cH:6][n:7]([CH2:35][C:36]3([CH2:39][O:40][Si:41]([CH3:42])([CH3:43])[C:44]([CH3:45])([CH3:46])[CH3:47])[CH2:37][CH2:38]3)[c:8](=[O:12])[c:9]2[cH:10][cH:11]1