Dichloromethane → 6-Methyl-5-[(1-methylethyl)oxy]-1-(4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one

반응식

[CH3:1][c:2]1[c:3]([O:25][CH:26]([CH3:27])[CH3:28])[cH:4][c:5]2[c:6]([n:7]([CH:11]3[CH2:12][CH2:13][N:14]([C:17]([O:18][C:19]([CH3:20])([CH3:21])[CH3:22])=[O:23])[CH2:15][CH2:16]3)[c:8](=[O:10])[nH:9]2)[cH:24]1.[Cl:36][CH2:37][Cl:38].[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35]>>[CH3:1][c:2]1[c:3]([O:25][CH:26]([CH3:27])[CH3:28])[cH:4][c:5]2[c:6]([n:7]([CH:11]3[CH2:12][CH2:13][NH:14][CH2:15][CH2:16]3)[c:8](=[O:10])[nH:9]2)[cH:24]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 598501771,1-Dimethylethyl 4-{6-methyl-5-[(1-methylethyl)oxy]-2-oxo-2,3-dihydro-1H-benzimidazol-1-yl}-1-piperidinecarboxylate

생성물 1

HCID 598501546-Methyl-5-[(1-methylethyl)oxy]-1-(4-piperidinyl)-1,3-dihydro-2H-benzimidazol-2-one

출처 및 근거

ORD 기록: ord-c93412f26f2e41a5b4388fd7618c8eb0
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

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