Dichloromethane → 5-{2-[5-Chloro-2-(hydroxy)-phenyl]cyclopent-1-enyl}-nicotinic Acid Ethyl Ester

반응식

[B:26]([Br:27])([Br:28])[Br:29].[CH2:1]([CH3:2])[O:3][C:4]([c:5]1[cH:6][n:7][cH:8][c:9]([C:11]2=[C:12]([c:16]3[c:17]([O:23][CH3:24])[cH:18][cH:19][c:20]([Cl:22])[cH:21]3)[CH2:13][CH2:14][CH2:15]2)[cH:10]1)=[O:25].[Cl:30][CH2:31][Cl:32]>>[CH2:1]([CH3:2])[O:3][C:4]([c:5]1[cH:6][n:7][cH:8][c:9]([C:11]2=[C:12]([c:16]3[c:17]([OH:23])[cH:18][cH:19][c:20]([Cl:22])[cH:21]3)[CH2:13][CH2:14][CH2:15]2)[cH:10]1)=[O:25]

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 25134Boron tribromide

HCID 695075875-{2-[5-Chloro-2-(methoxy)-phenyl]-cyclopent-1-enyl}-nicotinic acid ethyl ester

생성물 1

HCID 695077915-{2-[5-Chloro-2-(hydroxy)-phenyl]cyclopent-1-enyl}-nicotinic Acid Ethyl Ester

출처 및 근거

ORD 기록: ord-18f3d1ec60b945098975b524d4ee3197
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

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