2-Methyl-6-(4-trifluoromethyl-phenyl)-nicotinic acid → 2-[3-Methoxy-5-(2-{[2-methyl-6-(4-trifluoromethyl-phenyl)-pyridine-3-carbonyl]-amino}-ethyl)-phenoxy]-2-methyl-propionic acid ethyl ester

반응식

[CH2:1]([CH3:2])[O:3][C:4]([C:5]([CH3:6])([CH3:7])[O:8][c:9]1[cH:10][c:11]([CH2:17][CH2:18][NH2:19])[cH:12][c:13]([O:15][CH3:16])[cH:14]1)=[O:20].[CH3:21][c:22]1[c:23]([C:24](=[O:25])[OH:26])[cH:27][cH:28][c:29](-[c:31]2[cH:32][cH:33][c:34]([C:37]([F:38])([F:39])[F:40])[cH:35][cH:36]2)[n:30]1.[CH3:41][O:42][C:43](=[O:44])[c:45]1[cH:46][cH:47][c:48](-[c:49]2[cH:50][cH:51][c:52]([C:53]([F:54])([F:55])[F:56])[cH:57][cH:58]2)[n:59][c:60]1[CH3:61]>>[CH2:1]([CH3:2])[O:3][C:4]([C:5]([CH3:6])([CH3:7])[O:8][c:9]1[cH:10][c:11]([CH2:17][CH2:18][NH:19][C:24]([c:23]2[c:22]([CH3:21])[n:30][c:29](-[c:31]3[cH:32][cH:33][c:34]([C:37]([F:38])([F:39])[F:40])[cH:35][cH:36]3)[cH:28][cH:27]2)=[O:25])[cH:12][c:13]([O:15][CH3:16])[cH:14]1)=[O:20]