Bis-(4-methoxybenzyl)-[5-(2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-yl]-amine → 4-[4-[2-[bis[(4-methoxyphenyl)methyl]amino]pyrimidin-5-yl]-2-morpholin-4-yl-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]-3-fluoro-N-methyl-N-(2-morpholin-4-ylethyl)benzamide

HRID 112457

반응식

[Br:1][c:2]1[c:3]([F:20])[cH:4][c:5]([C:6](=[O:7])[N:8]([CH2:9][CH2:10][N:11]2[CH2:12][CH2:13][O:14][CH2:15][CH2:16]2)[CH3:17])[cH:18][cH:19]1.[CH3:21][O:22][c:23]1[cH:24][cH:25][c:26]([CH2:27][N:28]([c:29]2[n:30][cH:31][c:32](-[c:35]3[c:36]4[c:37]([n:38][c:39]([N:41]5[CH2:42][CH2:43][O:44][CH2:45][CH2:46]5)[n:40]3)[NH:47][CH2:48][CH2:49]4)[cH:33][n:34]2)[CH2:50][c:51]2[cH:52][cH:53][c:54]([O:57][CH3:58])[cH:55][cH:56]2)[cH:59][cH:60]1>>[c:2]1([N:47]2[c:37]3[c:36]([c:35](-[c:32]4[cH:31][n:30][c:29]([N:28]([CH2:27][c:26]5[cH:25][cH:24][c:23]([O:22][CH3:21])[cH:60][cH:59]5)[CH2:50][c:51]5[cH:52][cH:53][c:54]([O:57][CH3:58])[cH:55][cH:56]5)[n:34][cH:33]4)[n:40][c:39]([N:41]4[CH2:42][CH2:43][O:44][CH2:45][CH2:46]4)[n:38]3)[CH2:49][CH2:48]2)[c:3]([F:20])[cH:4][c:5]([C:6](=[O:7])[N:8]([CH2:9][CH2:10][N:11]2[CH2:12][CH2:13][O:14][CH2:15][CH2:16]2)[CH3:17])[cH:18][cH:19]1

참가 물질

반응물 2

HCID 45258862Bis-(4-methoxybenzyl)-[5-(2-morpholin-4-yl-6,7-dihydro-5H-pyrrolo[2,3-d]pyrimidin-4-yl)-pyrimidin-2-yl]-amine

HCID 673857524-bromo-3-fluoro-N-methyl-N-(2-morpholin-4-ylethyl)benzamide

생성물 1

HCID 685583144-[4-[2-[bis[(4-methoxyphenyl)methyl]amino]pyrimidin-5-yl]-2-morpholin-4-yl-5,6-dihydropyrrolo[2,3-d]pyrimidin-7-yl]-3-fluoro-N-methyl-N-(2-morpholin-4-ylethyl)benzamide

출처 및 근거

ORD 기록: ord-526acf578e2341c5a3d06b8ced11283c
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

연결된 노트

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