7-Isoquinolinol → Ditert-butyl 4-isoquinolin-7-yloxypyrrolidine-1,2-dicarboxylate

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:10][CH:11]([OH:13])[CH2:12]1.[cH:21]1[n:22][cH:23][cH:24][c:25]2[cH:26][cH:27][c:28]([OH:31])[cH:29][c:30]12>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:10][CH:11]([O:13][c:28]2[cH:27][cH:26][c:25]3[cH:24][cH:23][n:22][cH:21][c:30]3[cH:29]2)[CH2:12]1

참가 물질

반응물 2

HCID 4597677-Isoquinolinol

HCID 18967914Boc-D-hydroxyproline tert-butyl ester

생성물 1

HCID 67557732Ditert-butyl 4-isoquinolin-7-yloxypyrrolidine-1,2-dicarboxylate

출처 및 근거

ORD 기록: ord-a4fa9facf8e2440bb7706b57287ed50f
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

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