Alanine, methyl ester, hydrochloride (1:1) → 2-Cycloheptanoylaminopropionic acid

반응식

Cl.C[O:3][C:4](=[O:8])[CH:5]([CH3:7])[NH2:6].[CH:9]1([C:16](Cl)=[O:17])[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1>>[CH:9]1([C:16]([NH:6][CH:5]([CH3:7])[C:4]([OH:3])=[O:8])=[O:17])[CH2:15][CH2:14][CH2:13][CH2:12][CH2:11][CH2:10]1

참가 물질

반응물 2

HCID 2756298Alanine, methyl ester, hydrochloride (1:1)

HCID 12556870Cycloheptanecarbonyl chloride

생성물 1

HCID 228932292-Cycloheptanoylaminopropionic acid

실험 절차

The preparation is carried out analogously to the procedure of example 4A using 20 g (143 mmol) of D,L-alanine methyl ester hydrochloride and 23.02 g (143 mmmol) of cycloheptanoyl chloride.

출처 및 근거

ORD 기록: ord-97843fa2913f49ca9a50bf40eb014f8f
출처 데이터셋: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07098207B2

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