Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → 2-[5-(4-n-Butoxybenzenesulfonylamino)-2-ethoxyphenyl]-5-methyl-7-cyclopentyl-3H-imidazo-[5,1-f][1,2,4]-triazin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | 4-Butoxybenzenesulfonyl Chloride | HCID 517990 | — |
| 반응물 | 2-(5-Amino-2-ethoxyphenyl)-5-methyl-7-cyclopentyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-one | HCID 135604941 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-[5-(4-n-Butoxybenzenesulfonylamino)-2-ethoxyphenyl]-5-methyl-7-cyclopentyl-3H-imidazo-[5,1-f][1,2,4]-triazin-4-one | HCID 135604938 | — |
반응 단계
150 mg (0.424 mmol) of the compound from example 42A are reacted with 186 mg (0.747 mmol) of 4-(n-butoxy)-benzenesulfonyl chloride and 0.34 g (4.30 mmol) of pyridine in 6 ml of tetrahydrofuran.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07098207B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-19738cf49f484ac1b29bcf3080bba171 |
| 출처 메모 | uspto-grants-2006_08 |