Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Pyridine → 2-[5-(3-Chloropropanesulfonamido)-2-propoxyphenyl]-5-methyl-7-cyclopentyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Pyridine | HCID 1049 | — |
| 반응물 | 3-Chloropropanesulphonyl chloride | HCID 15410 | — |
| 반응물 | 2-(5-Amino-2-propoxyphenyl)-5-methyl-7-cyclopentyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-one | HCID 135604925 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | 2-[5-(3-Chloropropanesulfonamido)-2-propoxyphenyl]-5-methyl-7-cyclopentyl-3H-imidazo[5,1-f][1,2,4]-triazin-4-one | HCID 135604966 | — |
반응 단계
368 mg (1.0 mmol) of the compound from example 44A are reacted with 266 mg (1.5 mmol) of 3-chloropropanesulfonyl chloride and 0.81 ml (10.0 mmol) of pyridine in 12 ml of dichloromethane for 3 hours.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07098207B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-8f314dafc04e4e4c80a2a27202844908 |
| 출처 메모 | uspto-grants-2006_08 |