Pyridine → 3-chloro-N-[2-hydroxy-5-(pentafluoroethyl)phenyl]isonicotinamide

반응식

[Cl:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][n:9][cH:10]1.[NH2:11][c:12]1[c:13]([OH:25])[cH:14][cH:15][c:16]([C:18]([C:19]([F:20])([F:21])[F:22])([F:23])[F:24])[cH:17]1.[cH:26]1[cH:27][cH:28][n:29][cH:30][cH:31]1>>[Cl:1][c:2]1[c:3]([C:4](=[O:6])[NH:11][c:12]2[c:13]([OH:25])[cH:14][cH:15][c:16]([C:18]([C:19]([F:20])([F:21])[F:22])([F:23])[F:24])[cH:17]2)[cH:7][cH:8][n:9][cH:10]1

참가 물질

반응물 3

HCID 1049Pyridine

HCID 27358163-Chloropyridine-4-carboxylic acid

HCID 866510632-Amino-4-(pentafluoroethyl)phenol

생성물 1

HCID 866510493-chloro-N-[2-hydroxy-5-(pentafluoroethyl)phenyl]isonicotinamide

출처 및 근거

ORD 기록: ord-9b54da78bb4e46a6bb978527049ec6fa
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

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