Dichloromethane → [1-(2-Amino-3-phenylpropyl)piperidin-4-yl]-(4-fluorophenyl)methanone

반응식

[C:1]([O:2][C:3](=[O:4])[NH:7][CH:8]([CH2:9][N:10]1[CH2:11][CH2:12][CH:13]([C:16]([c:17]2[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]2)=[O:24])[CH2:14][CH2:15]1)[CH2:25][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1)([CH3:5])([CH3:6])[CH3:32].[Cl:40][CH2:41][Cl:42].[OH:33][C:34]([C:35]([F:36])([F:37])[F:38])=[O:39]>>[NH2:7][CH:8]([CH2:9][N:10]1[CH2:11][CH2:12][CH:13]([C:16]([c:17]2[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]2)=[O:24])[CH2:14][CH2:15]1)[CH2:25][c:26]1[cH:27][cH:28][cH:29][cH:30][cH:31]1

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 6422Trifluoroacetic acid

HCID 68815866tert-butyl N-[1-[4-(4-fluorobenzoyl)piperidin-1-yl]-3-phenylpropan-2-yl]carbamate

생성물 1

HCID 9945901[1-(2-Amino-3-phenylpropyl)piperidin-4-yl]-(4-fluorophenyl)methanone

출처 및 근거

ORD 기록: ord-2779c3b5c5b04884bd35af60894dddae
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…