2-(3-Fluorophenyl)pyrimidine-5-carboxylic acid → 2-(3-Fluoro-phenyl)-pyrimidine-5-carboxylic acid (4-cyclopentyl-piperazin-1-yl)-amide

반응식

[CH:17]1([N:22]2[CH2:23][CH2:24][N:25]([NH-:28])[CH2:26][CH2:27]2)[CH2:18][CH2:19][CH2:20][CH2:21]1.[F:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][cH:10][c:11]([C:14](=[O:15])[OH:16])[cH:12][n:13]2)[cH:5][cH:6][cH:7]1>>[F:1][c:2]1[cH:3][c:4](-[c:8]2[n:9][cH:10][c:11]([C:14](=[O:16])[NH:28][N:25]3[CH2:24][CH2:23][N:22]([CH:17]4[CH2:18][CH2:19][CH2:20][CH2:21]4)[CH2:27][CH2:26]3)[cH:12][n:13]2)[cH:5][cH:6][cH:7]1

참가 물질

반응물 2

HCID 450733632-(3-Fluorophenyl)pyrimidine-5-carboxylic acid

HCID 866393724-Cyclopentyl-piperazin-1-yl-amide

생성물 1

HCID 250993932-(3-Fluoro-phenyl)-pyrimidine-5-carboxylic acid (4-cyclopentyl-piperazin-1-yl)-amide

출처 및 근거

ORD 기록: ord-86a4aac41e5c42bcb2c799848c215e49
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

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