Dichloromethane → 4-{(5-Chloro-3-methyl-pyridin-2-ylmethyl)-[3-(1-methyl-1-phenyl-ethyl)-pyridin-2-ylmethyl]-amino}-piperidine-1-carboxylic acid tert-butyl ester

반응식

[C:18]([CH3:19])([CH3:20])([CH3:21])[O:22][C:23](=[O:24])[N:25]1[CH2:26][CH2:27][CH:28]([NH:31][CH2:32][c:33]2[n:34][cH:35][c:36]([Cl:40])[cH:37][c:38]2[CH3:39])[CH2:29][CH2:30]1.[CH3:1][C:2]([CH3:3])([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[c:10]1[c:11]([CH:16]=[O:17])[n:12][cH:13][cH:14][cH:15]1.[Cl:41][CH2:42][Cl:43]>>[CH3:1][C:2]([CH3:3])([c:4]1[cH:5][cH:6][cH:7][cH:8][cH:9]1)[c:10]1[c:11]([CH2:16][N:31]([CH:28]2[CH2:27][CH2:26][N:25]([C:23]([O:22][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:24])[CH2:30][CH2:29]2)[CH2:32][c:33]2[n:34][cH:35][c:36]([Cl:40])[cH:37][c:38]2[CH3:39])[n:12][cH:13][cH:14][cH:15]1