Methyl 4-(3-bromopropyl)benzoate → 4-(3-{2-[3-(Tert-butyl-dimethyl-silanyloxy)-4-(4-fluoro-phenyl)-butyl]-5-oxo-pyrrolidin-1-yl}-propyl)-benzoic acid methyl ester

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]([CH2:8][CH2:9][CH:10]1[CH2:11][CH2:12][C:13](=[O:15])[NH:14]1)[CH2:16][c:17]1[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]1)([CH3:24])[CH3:25].[CH3:26][O:27][C:28]([c:29]1[cH:30][cH:31][c:32]([CH2:35][CH2:36][CH2:37][Br:38])[cH:33][cH:34]1)=[O:39]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]([CH2:8][CH2:9][CH:10]1[CH2:11][CH2:12][C:13](=[O:15])[N:14]1[CH2:37][CH2:36][CH2:35][c:32]1[cH:31][cH:30][c:29]([C:28]([O:27][CH3:26])=[O:39])[cH:34][cH:33]1)[CH2:16][c:17]1[cH:18][cH:19][c:20]([F:23])[cH:21][cH:22]1)([CH3:24])[CH3:25]

참가 물질

반응물 2

HCID 10801120Methyl 4-(3-bromopropyl)benzoate

HCID 227125205-[3-(Tert-butyl-dimethyl-silanyloxy)4-(4-fluoro-phenyl)-butyl]-pyrrolidin-2-one

생성물 1

HCID 692689634-(3-{2-[3-(Tert-butyl-dimethyl-silanyloxy)-4-(4-fluoro-phenyl)-butyl]-5-oxo-pyrrolidin-1-yl}-propyl)-benzoic acid methyl ester

출처 및 근거

ORD 기록: ord-71e7c605f66c4003a07e0faf6ef11561
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

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