Dibenzylamine → 2-Dibenzylamino-3-nitropyridin-4-amine

반응식

[N+:1]([C:4]1[C:5](S([O-])(=O)=O)=[N:6][CH:7]=[CH:8][C:9]=1[NH2:10])([O-:3])=[O:2].[CH2:15]([NH:22][CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1>>[CH2:23]([N:22]([CH2:15][C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1)[C:5]1[C:4]([N+:1]([O-:3])=[O:2])=[C:9]([NH2:10])[CH:8]=[CH:7][N:6]=1)[C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1

참가 물질

반응물 2

HCID 7656Dibenzylamine

HCID 219738273-Nitro-4-aminopyridine-2-sulfonate

생성물 1

HCID 219738292-Dibenzylamino-3-nitropyridin-4-amine

실험 절차

In step (2) of Reaction Scheme I a 3-nitro-4-aminopyridine-2-sulfonate of Formula XI is reacted with dibenzylamine to provide a 2-dibenzylamino-3-nitropyridin-4-amine of Formula XII. The reaction is carried out by combining a compound of Formula XI, dibenzylamine, and a tertiary amine such as triethylamine in an inert solvent such as benzene, toluene or xylene and heating the resulting mixture.

출처 및 근거

ORD 기록: ord-40fed3ffbffa447ab223a880ae23ab39
출처 데이터셋: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07098221B2

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