Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Phenol → 3-Nitro-2-phenoxypyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Phenol | HCID 996 | — |
| 반응물 | 2-Chloro-3-nitropyridine | HCID 79613 | — |
| 생성물 | 3-Nitro-2-phenoxypyridine | HCID 901896 | — |
반응 단계
In step (3) of Reaction Scheme IV a 2-chloro-3-nitropyridine of Formula XXIV is reacted with phenol to provide a 3-nitro-2-phenoxypyridine of Formula XXV. Phenol is reacted with sodium hydride in a suitable solvent such as diglyme or tetrahydrofuran to form the phenoxide. The phenoxide is then reacted at ambient temperature, or optionally at an elevated temperature, with a compound of Formula XXIV.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07098221B2 |
| 출처 데이터셋 | uspto-grants-2006_08 |
| ORD ID | ord-8fb2123c92c44b8f9bd0be7e995b3f32 |
| 출처 메모 | uspto-grants-2006_08 |