Dichloromethane → 2-[1-(3,5-Dichloro-2-hydroxy-benzyl)-4-fluoro-piperidin-4-ylmethyl]-isoindole-1,3-dione

HRID 113672노트

반응식

[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[Cl:34][c:35]1[c:36]([OH:44])[c:37]([CH:38]=[O:39])[cH:40][c:41]([Cl:43])[cH:42]1.[Cl:45][CH2:46][Cl:47].[F:15][C:16]1([CH2:22][N:23]2[C:24](=[O:33])[c:25]3[cH:26][cH:27][cH:28][cH:29][c:30]3[C:31]2=[O:32])[CH2:17][CH2:18][NH:19][CH2:20][CH2:21]1.[OH:8][C:9]([C:10]([F:11])([F:12])[F:13])=[O:14]>>[F:15][C:16]1([CH2:22][N:23]2[C:24](=[O:33])[c:25]3[cH:26][cH:27][cH:28][cH:29][c:30]3[C:31]2=[O:32])[CH2:17][CH2:18][N:19]([CH2:38][c:37]2[c:36]([OH:44])[c:35]([Cl:34])[cH:42][c:41]([Cl:43])[cH:40]2)[CH2:20][CH2:21]1