Chloride → 4-(Hydroxy-quinolin-2-yl-methyl)-4-propyl-piperidine-1-carboxylic acid tert-butyl ester

HRID 1138912노트

반응식

[C:17]([CH3:18])([CH3:19])([CH3:20])[O:21][C:22](=[O:23])[N:24]1[CH2:25][CH2:26][C:27]([CH2:30][CH2:31][CH3:32])([CH:33]=[O:34])[CH2:28][CH2:29]1.[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH:13]([Mg+:14])([CH3:15])[CH3:16].[Cl-:12].[I:1][c:2]1[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[cH:10][cH:11]1>>[c:2]1([CH:33]([C:27]2([CH2:30][CH2:31][CH3:32])[CH2:26][CH2:25][N:24]([C:22]([O:21][C:17]([CH3:18])([CH3:19])[CH3:20])=[O:23])[CH2:29][CH2:28]2)[OH:34])[n:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]2[cH:10][cH:11]1