1-Iodopropane → methyl N-propyl-4-iodo-2-pyrrolecarboxylate

반응식

[I:1][C:2]1[CH:3]=[C:4]([C:7]([O:9][CH3:10])=[O:8])[NH:5][CH:6]=1.I[CH2:12][CH2:13][CH3:14]>>[CH2:12]([N:5]1[CH:6]=[C:2]([I:1])[CH:3]=[C:4]1[C:7]([O:9][CH3:10])=[O:8])[CH2:13][CH3:14]

참가 물질

반응물 2

HCID 336431-Iodopropane

HCID 11673249methyl 4-iodo-1H-pyrrole-2-carboxylate

생성물 1

HCID 19694682methyl N-propyl-4-iodo-2-pyrrolecarboxylate수율 64.7%

실험 절차

Following the basic procedure of Example 7(d), by reacting 1.96 g (7.8 mmol) of methyl 4-iodo-2-pyrrolecarboxylate with 940 μl (9.6 mmol) of 3-iodopropane, 1.48 g (64%) of methyl N-propyl-4-iodo-2-pyrrolecarboxylate was obtained in the form of a slightly yellow oil.

출처 및 근거

ORD 기록: ord-5fa351dbe3ea452bbf01e7f31dec9368
출처 데이터셋: uspto-grants-1998_03
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05723499

반응 노트

불러오는 중…