Trifluoroacetic acid → N-(5-(3-amino-4-fluorophenoxy)[1,3]thiazolo[5,4-b]pyridin-2-yl]acetamide

반응식

[C:1]([N:5]([C:2](=[O:3])[O-:4])[c:9]1[c:10]([F:29])[cH:11][cH:12][c:13]([O:15][c:16]2[cH:17][cH:18][c:19]3[c:20]([n:21]2)[s:22][c:23]([NH:25][C:26]([CH3:27])=[O:28])[n:24]3)[cH:14]1)([CH3:6])([CH3:7])[CH3:8].[OH:30][C:31]([C:32]([F:33])([F:34])[F:35])=[O:36]>>[NH2:5][c:9]1[c:10]([F:29])[cH:11][cH:12][c:13]([O:15][c:16]2[cH:17][cH:18][c:19]3[c:20]([n:21]2)[s:22][c:23]([NH:25][C:26]([CH3:27])=[O:28])[n:24]3)[cH:14]1

참가 물질

반응물 2

HCID 6422Trifluoroacetic acid

HCID 178474395N-[5-[(2-acetamido-[1,3]thiazolo[5,4-b]pyridin-5-yl)oxy]-2-fluorophenyl]-N-tert-butylcarbamate

생성물 1

HCID 86646025N-(5-(3-amino-4-fluorophenoxy)[1,3]thiazolo[5,4-b]pyridin-2-yl]acetamide

출처 및 근거

ORD 기록: ord-f97bf94d9add47ba8fcbc404ba9588cf
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

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