Acetonitrile → 3,4-difluoro-2-(2-fluoro-4-iodo-phenylamino)-N-(2-hydroxy-ethoxy)-5-(2-oxo-tetrahydro-pyrimidin-1-ylmethyl)-benzamide

반응식

[CH2:38]1[CH2:40][CH2:39][CH2:41][O:42]1.[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[CH3:43][C:44]#[N:45].[NH2:1][CH2:2][CH2:3][CH2:4][NH:5][CH2:6][c:7]1[c:8]([F:30])[c:9]([F:29])[c:10]([NH:20][c:21]2[c:22]([F:28])[cH:23][c:24]([I:27])[cH:25][cH:26]2)[c:11]([C:12](=[O:13])[NH:14][O:15][CH2:16][CH2:17][OH:18])[cH:19]1>>[NH:1]1[CH2:2][CH2:3][CH2:4][N:5]([CH2:6][c:7]2[c:8]([F:30])[c:9]([F:29])[c:10]([NH:20][c:21]3[c:22]([F:28])[cH:23][c:24]([I:27])[cH:25][cH:26]3)[c:11]([C:12](=[O:13])[NH:14][O:15][CH2:16][CH2:17][OH:18])[cH:19]2)[C:41]1=[O:42]