(Pyridin-4-yl)boronic acid → (2,6-Difluoro-4-pyridin-4-ylphenyl)-[2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone

HRID 1146676

반응식

HRID 1146676 반응식
[Br:1][c:2]1[cH:3][c:4]([F:22])[c:5]([C:9](=[O:10])[N:11]2[CH:12]([CH2:16][N:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[CH2:13][CH2:14][CH2:15]2)[c:6]([F:8])[cH:7]1.[n:23]1[cH:24][cH:25][c:26]([B:29]([OH:30])[OH:31])[cH:27][cH:28]1>>[c:2]1(-[c:26]2[cH:25][cH:24][n:23][cH:28][cH:27]2)[cH:3][c:4]([F:22])[c:5]([C:9](=[O:10])[N:11]2[CH:12]([CH2:16][N:17]3[CH2:18][CH2:19][CH2:20][CH2:21]3)[CH2:13][CH2:14][CH2:15]2)[c:6]([F:8])[cH:7]1

참가 물질

3

반응물 2

HCID 2734379(Pyridin-4-yl)boronic acidHCID 11964889(4-Bromo-2,6-difluorophenyl)-[2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone

생성물 1

HCID 11710466(2,6-Difluoro-4-pyridin-4-ylphenyl)-[2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]methanone

출처 및 근거

ORD 기록
ord-e5e651c71cf74281bda46193ecc806cb
출처 데이터셋
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

연결된 노트

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