1-(3,5-Dichloropyridin-2-yl)piperazine → (RS)-1-Benzenesulfonyl-3-cyclohexyl-4-[4-(3,5-dichloro-pyridin-2-yl)-piperazine-1-carbonyl]-imidazolidin-2-one

반응식

[Cl:25][c:26]1[c:27]([N:33]2[CH2:34][CH2:35][NH:36][CH2:37][CH2:38]2)[n:28][cH:29][c:30]([Cl:32])[cH:31]1.[c:1]1([S:7](=[O:8])(=[O:9])[N:10]2[C:11](=[O:24])[N:12]([CH:18]3[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[CH:13]([C:15](=[O:16])[OH:17])[CH2:14]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([S:7](=[O:8])(=[O:9])[N:10]2[C:11](=[O:24])[N:12]([CH:18]3[CH2:19][CH2:20][CH2:21][CH2:22][CH2:23]3)[CH:13]([C:15](=[O:16])[N:36]3[CH2:35][CH2:34][N:33]([c:27]4[c:26]([Cl:25])[cH:31][c:30]([Cl:32])[cH:29][n:28]4)[CH2:38][CH2:37]3)[CH2:14]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

참가 물질

반응물 2

HCID 27714311-(3,5-Dichloropyridin-2-yl)piperazine

HCID 67141201(RS)-1-benzenesulfonyl-3-cyclohexyl-2-oxo-imidazolidine-4-carboxylic acid

생성물 1

HCID 25029526(RS)-1-Benzenesulfonyl-3-cyclohexyl-4-[4-(3,5-dichloro-pyridin-2-yl)-piperazine-1-carbonyl]-imidazolidin-2-one

출처 및 근거

ORD 기록: ord-651e0980fc314261affa67dc731ea4fe
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

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