1-(4-Hydroxypiperidin-1-yl)ethan-1-one → 4-[2-(1-Acetyl-piperidin-4-yloxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester

반응식

[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]([OH:20])[cH:16][cH:17][cH:18][cH:19]2)[CH2:12][CH2:13]1.[OH:21][CH:22]1[CH2:23][CH2:24][N:25]([C:28]([CH3:29])=[O:30])[CH2:26][CH2:27]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[c:15]([O:20][CH:22]3[CH2:23][CH2:24][N:25]([C:28]([CH3:29])=[O:30])[CH2:26][CH2:27]3)[cH:16][cH:17][cH:18][cH:19]2)[CH2:12][CH2:13]1

참가 물질

반응물 2

HCID 107492911-(4-Hydroxypiperidin-1-yl)ethan-1-one

HCID 11543684Tert-butyl 4-(2-hydroxyphenyl)piperazine-1-carboxylate

생성물 1

HCID 694190504-[2-(1-Acetyl-piperidin-4-yloxy)-phenyl]-piperazine-1-carboxylic acid tert-butyl ester

출처 및 근거

ORD 기록: ord-956e914256794d7692db68df4955701c
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

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