Dichloromethane → 4-Chloro-7-(2-fluoro-4-methylsulfonylphenyl)-6-methyl-5,6-dihydropyrrolo[2,3-d]pyrimidine
반응식
[CH3:1][S:2]([O:3][CH2:4][CH2:5][c:6]1[c:7]([Cl:8])[n:9][cH:10][n:11][c:12]1[N:13]([C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[c:21]1[cH:22][cH:23][c:24]([S:25]([CH3:26])(=[O:27])=[O:28])[cH:29][c:30]1[F:31])(=[O:32])=[O:33].[CH3:57][CH2:58][N:59]([CH2:60][CH3:61])[CH2:62][CH3:63].[CH3:64][S:65]([O:66][S:67]([CH3:68])(=[O:69])=[O:70])(=[O:71])=[O:72].[Cl:34][c:35]1[n:36][cH:37][n:38][c:39]([NH:45][c:46]2[c:47]([F:56])[cH:48][c:49]([S:52](=[O:53])(=[O:54])[CH3:55])[cH:50][cH:51]2)[c:40]1[CH2:41][CH:42]([CH3:43])[OH:44].[Cl:73][CH2:74][Cl:75]>>[Cl:34][c:35]1[n:36][cH:37][n:38][c:39]2[c:40]1[CH2:41][CH:42]([CH3:43])[N:45]2[c:46]1[c:47]([F:56])[cH:48][c:49]([S:52](=[O:53])(=[O:54])[CH3:55])[cH:50][cH:51]1참가 물질
6
반응물 5
HCID 6344Dichloromethane
HCID 8471Triethylamine
HCID 81560Methanesulfonic anhydride
HCID 715402121-[4-Chloro-6-(2-fluoro-4-methylsulfonylanilino)pyrimidin-5-yl]propan-2-ol
HCID 86637380N-[6-chloro-5-[2-[(methylsulfonyl)oxy]ethyl]-4-pyrimidinyl]-N-[2-fluoro-4-(methylsulfonyl)phenyl]Carbamic acid 1,1-dimethylethyl ester생성물 1
