Dichloromethane → {3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonylazetidin-3-one

반응식

[CH3:25][CH2:26][O:27][C:28](=[O:29])[CH3:30].[Cl:31][CH2:32][Cl:33].[F:1][c:2]1[c:3]([NH:16][c:17]2[c:18]([F:24])[cH:19][c:20]([I:23])[cH:21][cH:22]2)[c:4]([C:9](=[O:10])[N:11]2[CH2:12][CH:13]([OH:15])[CH2:14]2)[cH:5][cH:6][c:7]1[F:8]>>[F:1][c:2]1[c:3]([NH:16][c:17]2[c:18]([F:24])[cH:19][c:20]([I:23])[cH:21][cH:22]2)[c:4]([C:9](=[O:10])[N:11]2[CH2:12][C:13](=[O:15])[CH2:14]2)[cH:5][cH:6][c:7]1[F:8]

참가 물질

반응물 3

HCID 6344Dichloromethane

HCID 8857Ethyl Acetate

HCID 16223325[3,4-Bis(Fluoranyl)-2-[(2-Fluoranyl-4-Iodanyl-Phenyl)amino]phenyl]-(3-Oxidanylazetidin-1-Yl)methanone

생성물 1

HCID 16223411{3,4-Difluoro-2-[(2-fluoro-4-iodophenyl)amino]phenyl}carbonylazetidin-3-one

출처 및 근거

ORD 기록: ord-709a27ab93fc4813a3eb60dfdf187963
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

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