5-(6-Bromo-2-phenyl-imidazo[1,2-a]pyridin-7-ylcarbamoyl)-1-methyl-1H-pyrazole-4-carboxylic acid → 1-Methyl-5-(5-morpholin-4-yl-2-phenyl-imidazo[1,2-c]pyrimidin-7-ylcarbamoyl)-1H-pyrazole-4-carboxylic acid

반응식

[Br:1][c:2]1[c:3]([NH:4][C:18](=[O:19])[c:20]2[c:21]([C:26](=[O:27])[OH:28])[cH:22][n:23][n:24]2[CH3:25])[cH:5][c:6]2[n:7]([cH:8][c:9](-[c:10]3[cH:11][cH:12][cH:13][cH:14][cH:15]3)[n:16]2)[cH:17]1.[O:29]1[CH2:30][CH2:31][N:32]([c:35]2[n:36][c:37]([NH2:50])[cH:38][c:39]3[n:40]2[cH:41][c:42](-[c:44]2[cH:45][cH:46][cH:47][cH:48][cH:49]2)[n:43]3)[CH2:33][CH2:34]1>>[C:18](=[O:19])([c:20]1[c:21]([C:26](=[O:27])[OH:28])[cH:22][n:23][n:24]1[CH3:25])[NH:50][c:37]1[n:36][c:35]([N:32]2[CH2:31][CH2:30][O:29][CH2:34][CH2:33]2)[n:40]2[c:39]([cH:38]1)[n:43][c:42](-[c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1)[cH:41]2

참가 물질

반응물 2

HCID 670416185-(6-Bromo-2-phenyl-imidazo[1,2-a]pyridin-7-ylcarbamoyl)-1-methyl-1H-pyrazole-4-carboxylic acid

HCID 670419775-Morpholin-4-yl-2-phenyl-imidazo[1,2-c]pyrimidin-7-ylamine

생성물 1

HCID 670422821-Methyl-5-(5-morpholin-4-yl-2-phenyl-imidazo[1,2-c]pyrimidin-7-ylcarbamoyl)-1H-pyrazole-4-carboxylic acid

출처 및 근거

ORD 기록: ord-470b35d94b524e25b6a98bd0ff1124c5
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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