Toluene → [5-oxo-6-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-7-propyl[1,2,4]triazolo[1,5-a]pyrimidin-4(5H)-yl]acetic acid

반응식

[CH3:48][c:49]1[cH:50][cH:51][cH:52][cH:53][cH:54]1.[O:1]=[c:2]1[n:3]([CH2:33][C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[c:4]2[n:5]([c:6]([CH2:27][CH2:28][CH3:29])[c:7]1[CH2:8][c:9]1[cH:10][cH:11][c:12](-[c:15]3[c:16](-[c:21]4[n:22][o:23][c:24](=[O:26])[nH:25]4)[cH:17][cH:18][cH:19][cH:20]3)[cH:13][cH:14]1)[n:30][cH:31][n:32]2.[OH:41][C:42]([C:43]([F:44])([F:45])[F:46])=[O:47]>>[O:1]=[c:2]1[n:3]([CH2:33][C:34](=[O:35])[OH:36])[c:4]2[n:5]([c:6]([CH2:27][CH2:28][CH3:29])[c:7]1[CH2:8][c:9]1[cH:10][cH:11][c:12](-[c:15]3[c:16](-[c:21]4[n:22][o:23][c:24](=[O:26])[nH:25]4)[cH:17][cH:18][cH:19][cH:20]3)[cH:13][cH:14]1)[n:30][cH:31][n:32]2