1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid → N-[4-(1-Benzylpiperidin-4-yloxy)-3-cyanophenyl]-1-(4-chlorophenyl)-5-methylpyrazole-4-carboxamide

반응식

[Cl:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][c:11]([C:14](=[O:15])[OH:16])[c:12]2[CH3:13])[cH:6][cH:7]1.[NH2:17][c:18]1[cH:19][cH:20][c:21]([O:26][CH:27]2[CH2:28][CH2:29][N:30]([CH2:33][c:34]3[cH:35][cH:36][cH:37][cH:38][cH:39]3)[CH2:31][CH2:32]2)[c:22]([C:23]#[N:24])[cH:25]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5](-[n:8]2[n:9][cH:10][c:11]([C:14](=[O:16])[NH:17][c:18]3[cH:19][cH:20][c:21]([O:26][CH:27]4[CH2:28][CH2:29][N:30]([CH2:33][c:34]5[cH:35][cH:36][cH:37][cH:38][cH:39]5)[CH2:31][CH2:32]4)[c:22]([C:23]#[N:24])[cH:25]3)[c:12]2[CH3:13])[cH:6][cH:7]1

참가 물질

반응물 2

HCID 27771661-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid

HCID 219423525-Amino-2-(1-benzylpiperidin-4-yloxy)benzonitrile

생성물 1

HCID 22228123N-[4-(1-Benzylpiperidin-4-yloxy)-3-cyanophenyl]-1-(4-chlorophenyl)-5-methylpyrazole-4-carboxamide

출처 및 근거

ORD 기록: ord-b7fae17d8f7b4c3e8896533871376846
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D

반응 노트

불러오는 중…