4-(2-(Diethylamino)ethoxy)aniline → HCID 178418699, 화합물
반응식
[CH2:1]([N:3]([CH2:14][CH3:15])[CH2:4][CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([NH2:13])=[CH:9][CH:8]=1)[CH3:2].[F:16][C:17]1[CH:25]=[C:24]2[C:20]([C:21](=[CH:27]O)[C:22](=[O:26])[NH:23]2)=[CH:19][CH:18]=1>>[CH2:14]([N:3]([CH2:1][CH3:2])[CH2:4][CH2:5][O:6][C:7]1[CH:8]=[CH:9][C:10]([NH:13][CH:27]=[C:21]2[C:20]3[C:24](=[CH:25][C:17]([F:16])=[CH:18][CH:19]=3)[NH:23][C:22]2=[O:26])=[CH:11][CH:12]=1)[CH3:15]참가 물질
3
실험 절차
In a manner similar to that described in Example 231, 4-(2-Diethylamino-ethoxy)-phenylamine (697 mg, 1.2 equiv.) and 6-fluoro-3-hydroxymethylene-1,3-dihydro-indol-2-one (500 mg, 2.79 mmol, 1 equiv.) are reacted to give the named compound as a yellow solid (399 mg, 39%).
후처리
- customare reacted
출처 및 근거
- ORD 기록
- ord-fbe1967216c44cbb8fff20d89bdee88c
- 출처 데이터셋
- uspto-grants-2006_08