Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1-Butanol → Benzenepropanol
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1-Butanol | HCID 263 | — |
| 반응물 | 1,1,2,2-Tetrachloroethane | HCID 6591 | — |
| 반응물 | Chlorine | HCID 24526 | — |
| 반응물 | 2,2-Dichlorobutanal | HCID 11275051 | — |
| 촉매 | N,N-dimethylformamide;hydrochloride | HCID 10920465 | — |
| 용매 | Isobutanol | HCID 6560 | — |
| 생성물 | Benzenepropanol | HCID 31234 | — |
반응 단계
n-Butanol and Cl2 were added concurrently to a 100 ml, four necked, round bottomed flask containing ~10 g of DMF/HCl catalyst and 25 ml of 1,1,2,2-tetrachloroethane. The temperature was maintained between 50° and 55° C. by controlling the rates of the addition. Upon completion of the addition, the reaction mixture was shown to contain mainly the product 2,2-dichlorobutyraldehyde by GC and NMR analysis. Similar results were obtained with isobutanol and 3-phenylpropanol. Analysis was in agreement with authentic products by GC, IR and NMR.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04486608 |
| 출처 데이터셋 | uspto-grants-1984_12 |
| ORD ID | ord-58577cdad3b14dbdae74e7181a87f133 |
| 출처 메모 | uspto-grants-1984_12 |