Formic Acid → HCID 13075532, 화합물

HRID 1153969노트

반응식

HRID 1153969 반응식
[I:1][C:2](=[C:5]([I:7])[I:6])[CH2:3][OH:4].[CH:8](O)=[O:9]>>[CH:8]([O:4][CH2:3][C:2]([I:1])=[C:5]([I:7])[I:6])=[O:9]

참가 물질

3

반응물 2

HCID 284Formic AcidHCID 102167312,3,3-Triiodoallyl alcohol

생성물 1

HCID 13075532HCID 13075532, 화합물

실험 절차

2.0 g of 2,3,3-triiodoallyl alcohol and 30 ml of formic acid were refluxed, with stirring, for 3 hours. After cooling the mixture, the crystals which precipitated were collected by filtration, dissolved in ethyl acetate, adsorbed in a dry silica gel chromatography column and eluted with 3:1 by volume mixture of hexane and ethyl acetate, to give 1.8 g of the desired Compound No. 81 in the form of crystals melting at 84°-85° C.

후처리

  1. temperatureAfter cooling the mixture
  2. customthe crystals which precipitated
  3. filtrationwere collected by filtration
  4. dissolutiondissolved in ethyl acetate
  5. washeluted with 3:1 by volume mixture of hexane and ethyl acetate

출처 및 근거

ORD 기록
ord-9967c43190c74e3fbd834ca8706d02c5
출처 데이터셋
uspto-grants-1984_12
특허 번호
US04487781

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